Antimetabolites

Drugs

• Capecitabine, Cladribine, Cytarabine, Floxuridine, Fludarabine, Flurouracil, Gemcitabine, Mercaptopurine, Methotrexate, Pentostatin, Thioguanine

What is it?

• Antimetabolites- Cause Cell Death, Block Cell Progression
• Used For- Acute/Chronic Myelocytic Leukemia, Acute/Chronic Lymphocytic Leukemia; Rheumatoid Arthritis, Cancer of the Breast, Colon, Pancreas, Stomach, Rectum; Non-Hodgkin’s Lymphoma in Children

Side Effects

• Fever, Rash, Freckling, Loss of Hair, Nausea, Vomiting, Diarrhea, Stomach Pain, Yellowing of the Skin, Acute Pancreatitis, Dizziness, Headache, Anal Inflammation, Weakness, Chest Pain, Difficulty Swallowing, Unusual Bruising or Bleeding, Chills, Sore Throat
• Mouth Care- for Mouth Sores

What can I do?

• See your Health Care Provider- as needed; Birth Control
• See your Pharmacist- for help
• AVOID- Taking with NSAIDs, Lactation, Impaired Liver Function, Allergic to Antimetabolites
• See a Food Fitness First Registered Dietitian- on line for help; Small/Frequent Meals, Increase Fluids